OVERVIEW
Better life, right tool
AgroRNA Long dsRNA Synthesis Service
RNA interference(RNAi) is a mechanism in which dsRNA inhibits gene function in a sequence specific manner.
RNA interference works in the cytoplasm of the cell; thus it does not genetically modify the organism. It can block and organism’s production of an essential protein and suppress or modify various genetic traits without changing the genetic make-up of the organism. It has been well known that long dsRNA (~200-800 bp) can initiate RNAi in plants, worms, insects, and even shrimp. Thus, dsRNA has been studied and can be a new raw material for herbicide, insecticide, anti-fungal and anti-viral applications for agricultural as well as environmental applications. Because of its sequence specificity, it can also be designed to have no toxicity to non-targeted organisms.
- Our product
- Synthesized via proprietary in-vitro transcription platform
- Free from any living organisms such as genetically modified E. coli with expresses dsRNA.
- Provided as pre-annealed duplex
- Provided with Agarose gel and Nanodrop analysis report
- Shipped at ambient temperature in liquid form
| Grade | Grade1 | Grade2 |
|---|---|---|
| Description | Unprocessed dsRNA mixture | Dissolved in water |
| Purification | No | Yes (Standard desalting) |
| Contains | dsRNA, enzymes, salts and major free NTP | dsRNA and minor inpurities |
| Synthesis Scale | 10 mg | 100 mg | 1 g | 10 g | 100 g | 1 kg |
|---|---|---|---|---|---|---|
| Guaranteed Amount* | > 70 % | > 50 % | ||||
| Turnaround Time | 5-6 weeks | 6-8 weeks** | 8-10 weeks** | |||
* Size from 200 to 800 bp / Pre-annealed as duplex
* Supplied amount may vary depending on the length of dsRNA. Generally, less amount will be provided for shorter dsRNA.
* * For Grade 1 products
Genolution AgroRNA dsRNA Synthesis Service Leaflet